- From Stockholm, the Royal Swedish Academy of Sciences confers the prizes for physics, chemistry, and economics, the Karolinska Institute confers the prize for physiology or medicine, and the Swedish Academy confers the prize for literature.
- T William Kaelin Jr at the Dana Farber Cancer Institute and Harvard University in Massachusetts; Sir Peter Ratcliffe at Oxford University and the Francis Crick Institute in London; and Gregg Semenza at Johns Hopkins University in Baltimore, Maryland, worked out how cells sense falling oxygen levels and respond by making new blood cells and vessels.
THE RESEARCH WORK
- The fundamental importance of oxygen has been understood for centuries, but how cells adapt to changes in oxygen levels has long been unknown. This year’s #NobelPrize awarded work reveals the molecular mechanisms that underlie how cells adapt to variations in oxygen supply.
- Oxygen sensing is central to a large number of diseases. The discoveries made by this year’s #NobelPrize laureates have fundamental importance for physiology and have paved the way for promising new strategies to fight anaemia, cancer and many other diseases.